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‪Karin Odelius‬ - ‪Google Scholar‬

Stimuli-responsive metal–organic framework nanoparticles, NMOFs, provide a versatile platform for the controlled release of drugs and biomedical applications. The porous structure of NMOFs, their biocompatibility, low toxicity, and efficient permeability turn the NMOFs into ideal carriers for therapeutic applications. 2018, Inbunden. Köp boken Stimuli-responsive Drug Delivery Systems hos oss! Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy Yiting Qiao The First Affiliated Hospital; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases; Key Laboratory of Combined Multi‐Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, P.R. China Potential stimuli and responses of synthetic stimuli-responsive polymers (adapted from Schmaljohann [6]). Stimuli-responsive polymeric drug delivery is another ﬁeld of controlled drug delivery.

The nanoprobes used were found to offer dual pH and temperature responsive drug delivery capability, and are specifically targeted to cancer cells which also shows intracellular MR based diagnostic and tracking ability. 2021-04-07 STIMULI-RESPONSIVE DRUG DELIVERY SYSTEMS BASED ON MESOPOROUS SILICA NANOPARTICLES WONG MUN FEI EDDY School of Physical and Mathematical Sciences A thesis submitted to the Nanyang Technological University in partial fulfilment of the requirement for the degree of Master of Science The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible. Implementation of such devices requires the use of biocompatible materials that are susceptible to a specifi … Pris: 1619 kr. Inbunden, 2018. Skickas inom 5-8 vardagar.

This particular work focuses on the smart chemistry and mechanism of action aspects of several types of stimuli-responsive … Stimuli-responsive hydrogels in drug delivery and tissue engineering Nikhil Sood, Ankur Bhardwaj, Shuchi Mehta, and Abhinav Mehta Nanomedicine Research Centre, ISF College of Pharmacy Ferozepur, Moga, Punjab, India Abstract Hydrogels are the three-dimensional network structures obtained from a … Magnetic‐responsive drug delivery is a unique technique using the influence of an external magnetic field, which cannot only precisely drive the drug‐loaded magnetic NPs to the intended site to improve therapeutic efficacy, but also serve as an external stimulus to trigger a controllable release of the drug… Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives Hossam S. El-Sawy Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 63514, Egypt Dendrimers have shown great promise as carriers in drug delivery due to their unique structures and superior properties. However, the precise control of payload release from a dendrimer matrix still presents a great challenge.

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In this study, we reviewed state-of-the-art endogenous-based and exogenous-based stimuli-responsive drug delivery systems (DDS) for programmed site-specific release to overcome the drawbacks of conventional therapeutic modalities. The use of polymeric nanocarriers for imaging and to deliver active compounds has attracted considerable interest in various cancer therapy fields. So-called smart nanopolymer systems are built to respond to certain stimuli such as temperature, pH, light intensity and wavelength, and electrical, magnetic and ultrasonic fields. Adv Drug Deliv Rev. 2013 Nov;65(13-14):1699-715.

Stimuli-responsive Drug Delivery Systems - Amit Singh, Mansoor M

The basic mechanisms of stimuli‐responsive drug delivery systems can be described as follows: after injection, the stimuli‐responsive drug delivery system (nanocarriers) accumulates at a tumor site via passive (enhanced permeability and retention effect) or active (receptor–ligand affinity) targeting. Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy Yiting Qiao The First Affiliated Hospital; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases; Key Laboratory of Combined Multi‐Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, P.R. China The discussion goes from stimuli‐responsive polymers with responsive backbones or modified by responsive functional groups for drug encapsulation and release to polymer–drug conjugates with responsive covalent linkages. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally. The stimuli-responsive nanocarriers for drug delivery to tumors towards precision imaging, effective therapy and theranostics. The nanocarriers could accumulate and penetrate tumors, and target cancer cells for achieving different applications and functions by responding to the external and internal stimuli.

GABA delivery stopped epileptiform activity, recorded simultaneously and colocally. habituation of the C-start in response to brief pulses of auditory stimuli. Phase-locked gamma band responses to semantic violation stimuli. Advanced Drug Delivery Reviews, 61(5) pp.
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In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The polymer architectures exhibiting a large change in their physico chemical behaviors in response to minor signals from the environments have fabricated potentially useful materials for pharmaceutical and biomedical applications. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally.

Relaterade stimuli är till för att komma på nya idéer genom and evaluation of their drug release profile, Polymer International, vol. responsive [1]. Drug treatment of depression in frail eld- erly nursing home triciteten, nämligen kortvariga fyrkantsvågor (brief pulse stimulus technique dopamine release in the caudate nucleus.
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In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally. Light is a popular choice as an external stimulus since its intensity and penetration depth can be precisely controlled.

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Sveriges lantbruksuniversitet - Primo - SLU-biblioteket

2020-02-01 · MOF-based stimuli-responsive drug delivery Due to the introduction of stimuli responsive groups or materials into MOF structure, such as imidazolyl (pH), disulfide bond (GSH), porphyrin (light) and etc., the smart materials will undergo molecular conformational changes, protonation or hydrolytic cleavage under stimuli, leading to the release of guest molecules [ 107 ]. Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible. In this study, we reviewed state-of-the-art endogenous-based and exogenous-based stimuli-responsive drug delivery systems (DDS) for programmed site-specific release to overcome the drawbacks of conventional therapeutic modalities. The use of polymeric nanocarriers for imaging and to deliver active compounds has attracted considerable interest in various cancer therapy fields.